アメリカ合衆国中毒センターレポートに見る家庭用フッ素入り歯科製品での事故報告

Fluoride Action Network より:

Reports to the American Association of Poison Control Centers Related to Fluoride-containing Dental Products and the Outcomes, 1989-1994 (Data from: Shulman 1997)
			# Treated in Health Care Facilities	Medical Outcome*
Year	Product	# Reports	# Treated in Health Care Facilities	None	Minor	Moderate	Major	Death
1989	Toothpaste	1,392	101	464	371	15	0	0
	Mouthrinse	1,185	56	503	115	3	0	0
	Supplements	4,028	375	1,807	663	14	1	1
	Vitamins**	3,153	184	1,214	135	0	0	0
1990	Toothpaste	1,379	107	468	329	7	0	0
	Mouthrinse	1,299	64	511	109	2	0	0
	Supplements	4,437	338	1,950	653	10	0	0
	Vitamins**	2,938	135	949	0	0	0	0
1991	Toothpaste	1,623	120	497	403	15	0	0
	Mouthrinse	1,418	72	556	112	0	0	0
	Supplements	4,350	368	1,593	667	12	0	0
	Vitamins**	2,741	102	595	93	3	0	0
1992	Toothpaste	2,331	141	700	497	17	1	0
	Mouthrinse	1,338	52	545	92	1	0	0
	Supplements	4,171	340	1,579	624	12	0	0
	Vitamins**	2,949	122	883	111	1	0	0
1993	Toothpaste	2,507	143	725	571	21	0	0
	Mouthrinse	1,144	52	409	75	4	0	0
	Supplements	3,483	249	1,143	503	16	0	1
	Vitamins**	2,650	105	706	100	0	0	0
1994	Toothpaste	3,369	166	852	800	19	1	0
	Mouthrinse	1,220	40	409	79	3	0	0
	Supplements	3,544	240	1,224	489	22	1	0
	Vitamins**	2,493	86	663	111	0	0	0
* No effect: No signs or symptoms as the result of exposure. Minor effect: Minimally bothersome signs or symptoms that generally resolved without residual disability or disfigurement (e.g. self-limiting gastrointestinal symptoms). Moderate effect: More pronounced or prolonged signs or symptoms, or more of a systemic nature than minor systems. While the symptoms are not life-threatening (e.g., disorientation or high fever that responds readily to treatment), some form of treatment is indicated. Major effect: Signs and symptoms that are life-threatening or result in significant residual disability or disfigurement. ** With fluoride but without iron.
SOURCE: Shulman JD, Wells LM. (1997). Acute fluoride toxicity from ingesting home-use dental products in children, birth to 6 years of age. Journal of Public Health Dentistry 57: 150-8.